John Samuel Pobee studied at Adisadel 1950-56 obtaining both the Cambridge School Certificate and Higher School Certificate. Subsequently, he studied at University of Ghana and Selwyn College, University of Cambridge. He had his priestly formation at Westcott House, Cambridge. At the University of Ghana, he was Head of Department for the Study of Religions, Dean of the Faculty of Arts, Admissions and Examinations.
He later worked at the World Council of Churches in Geneva. He was Emeritus Professor at the University of Ghana. He was married to Martha, a career diplomat of the Ghana Foreign Service.
He served as the Vicar-General of the Anglican Diocese of Accra.
Prof Pobee died in Ghana in January 2020 at the age of 82.